"United States Census, 1850," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:M442-49K : 21 December 2020), Jacob Kifsinger, Cumru Township, Berks, Pennsylvania, United States; citing family , NARA microfilm publication (Washington, D.C.: National Archives and Records Administration, n.d.).
"United States Census, 1880," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MWXM-CHT : 20 February 2021), Jacob Kissinger, Spring, Berks, Pennsylvania, United States; citing enumeration district ED 66, sheet 305A, NARA microfilm publication T9 (Washington, D.C.: National Archives and Records Administration, n.d.), FHL microfilm 1,255,100.
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It may be possible to confirm family relationships with Jacob by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Jacob: