This statement in the book seems to be unsupported.
Samuel Knox was the brother of John Knox who as the father of Jane Knox who married Samuel Polk and was the father of James Knox Polk, the 11th President of the United States. [1]
Samuel was born about 1743.
Sources
↑ The Taggarts of Brown County, Indiana : before and beyond, Susan Morris McGee, pg 94
The Taggarts of Brown County, Indiana : before and beyond, Susan Morris McGee, pg 93
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DNA Connections
It may be possible to confirm family relationships with Samuel by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Samuel:
Knox-3360 and Knox-3160 appear to represent the same person because: This is the same person. The date for marriage was based on the age of his wife. This person had at least three daughters. Mary Knox Pettus, Jane Knox Pettus and Sarah Knox Candish. He was married to Mary Taggart Knox.