Samuel (Jacob)'s wife, Mary, is living with her daughter's family in the 1860 US census, with no sign of her husband... therefore I have estimated his death date as before 1860. ( Freeth-52 17:01, 22 April 2016 (EDT) )
"United States Census, 1830," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:XHPY-S55 : accessed 24 April 2016), Saml D Lamb, Jackson, Alabama, United States; citing 131, NARA microfilm publication M19, (Washington D.C.: National Archives and Records Administration, n.d.), roll 1; FHL microfilm 2,328.
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It may be possible to confirm family relationships with Samuel by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Samuel: