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Note: easily confused with her sisters Marie and Madeleine. She is called Marguerite and Marie in existing records. Stephen White lists her first of the children born to René dit l'Aîné Landry and Perrine Bourg.
Marie Marguerite Landry, daughter of Rene dit l'Aîné Landry and Perrine Bourg, was born about 1646. (Census birth dates were 1647, 1651, 1649, 1649)
Germain (born 1641) and Marie were married about 1664 in Port-Royal, Acadia. Between about 1665 and 1685, the couple had nine children:
Five of her seven sons, all born at Port-Royal, created families of their own. Most of Marie's sons remained at Port-Royal, at least until Le Grand Dérangement.
Germain, a ploughman (laboureur) age 30, and Marie 24, were listed with their 3 sons in the first census of Port-Royal in 1671. They owned 11 head of cattle and 7 sheep.
The subsequent censuses of Port-Royal of 1686 and 1693 show how the household of Germain Doucet in Port-Royal and the family’s possessions varied with time.
Germain died before the census of 1698 at Port-Royal when Marie had already remarried to Etienne Comeau.  In the 1700 census Marie appears as the widow of Germain Doucet but is not listed as Étienne Comeau’s wife.  She is listed again in 1701, this time with Etienne. 
Marie passed away in Port-Royal according to the depositions of Belle-île-en-Mer  The exact date of death is not known. We know that she lived until at least 1701 since she was on the census. Certain family trees list the following dates for the date of death 26 Oct 1717 or 26 Oct 1719 but no records have been found to support this claim.
Marie LANDRY, daughter of Rene' & Perrine BOURG, born around 1646 [listed 1st of their children]. She married 1st around 1664 at Port-Royal (Belle-Ile-en-Mer Declaration) to Germain DOUCET, son of Germain; nine children. She married 2nd before the 1698 census to E'tienne COMEAU (widower of Marie-Anne LEFEBVRE. She died at Port Royal.
Estienne COMEAU 51, Marie LANDRY (wife) 55; Pierre 16; 9 guns, 15 cattle (this should probably he 9 cattle and 15 sheep), 6 hogs, 6 arpents.
↑ White, Stephen A. Origins of the Pioneers of Acadia, According to the Depositions made by Their Descendants at Belle-Ile-en-Mer in 1767 English Translation, Publication: University of Moncton, Centre d'études acadiennes; Online.
"On 9 March 1767 appeared Pierre DOUCET, living in Anvorte, Sauzon Parish, who, in presence of Joseph BABIN, Louis COURTIN, Simon P. DAIGRE and Jean B. LeBLANC, Acadians living on this island, witnesses, who stated he was born at the Mines, St. Charles Parish in November 1738 of Jean DOUCET and Magdelaine THERIOT of that place. Jean DOUCET was the son of Jean and Marie ROBICHAULT of Port Royal and Jean DOUCET was son of Charles and Hugette GUERIN. Charles DOUCET came from Germain DOUCET who came to Canada and married at Port Royal to Marguerite LANDRY. Both died at that place. Marie was daughter of Prudent ROBICHAULT and Henriette PETIPAS; Prudent ROBICHAULT was the son of Charles (from France with his wife) and who settled at Port Royal and died there."
It may be possible to confirm family relationships with Marie by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage (beta) of DNA with Marie: