Susanna "Susan" Licklider was born July 26, 1791, in Jefferson County, Virginia, a daughter of Conrad Leichleiter and Anna Margaretha (Froschauer) Leichleiter. Note: This portion of Virginia became West Virginia, in 1863, at the onset of the American Civil War. Susan married Samuel Darke Engle, a son of Joseph Engle and Sarah (Edmonson) Engle. Children of Susanna and Samuel are:
Margaret Engle, born September 20, 1819, died August 18, 1872
Joseph Engle, born May 16, 1821, died January 22, 1850
William Engle, born September 19, 1822, died December 12, 1853
Sarah Engle, born April 11, 1824, died young
Susan Engle, born January 18, 1827, died June 3, 1899
Thomas Engle, born February 8, 1829, died young
Benjamin Francis Engle, born June 7, 1830, died January 18, 1874, married Laura Lee Philips, moved to Ohio
George Washington Engle, born April 6, 1832, died December 8, 1895, married 1) Martha Grantham Hayslett and 2) Martha Montgomery Chapman (mother of all 13 of his children)
Samuel Darke Engle, II, born April 19, 1833, died December 16, 1899, married Jane Chapman
Susan, wife of Samuel D. Engle died September 8, 1875, in Jefferson county. 
Tradition is that Susan and her husband are buried in the Ronemous Engle Cemetery, in Shenandoah Junction, Jefferson County, West Virginia. 
↑ "West Virginia Deaths, 1804-1999," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:NMXQ-3VF : 11 February 2018), Licklider in entry for Susan Engle, 08 Sep 1875; citing Chast. D., Jefferson Co., West Virginia, County Records, 28, county courthouses, West Virginia; FHL microfilm 829,326
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It may be possible to confirm family relationships with Susan by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage (beta) of DNA with Susan: