Anne Lewis was possibly from the Jeremiah Lewis family. Parents are uncertain. David, a brother, or a cousin could have been her father, per DNA.
She married John Atwell 4 Sep 1797. Frederick County, MD. The marriage was in the right state, right time, and nothing further is found in Maryland about the John Atwell she married.
Anne passed away in 1807.
Sources
From research of Kathy Alvis Patterson at alvispat.wordpress.com/atwell-john-sr-of-md-and-nc/
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DNA Connections
It may be possible to confirm family relationships with Anne by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Anne: