Had two wives, Mary MacLeod is descended from the first one
Sources
Possible FindAGrave source for John Macleod, but no connection found.
Find a Grave, database and images (https://www.findagrave.com/memorial/192830234/john-macleod : accessed 9 April 2022), memorial page for John Macleod (1800–11 Nov 1863), Find A Grave: Memorial #192830234, citing Rosskeen Churchyard, Rosskeen , Highland, Scotland ; Maintained by sam crosbie (contributor 48795225).
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DNA Connections
It may be possible to confirm family relationships with John by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with John: