October 4, 1774 -- Frances Taylor Madison was born at Montpelier, Orange County, Virginia, a daughter of James Madison and Eleanor Rose Conway. Frances was the last of 12 children and the last of four daughters. 
January 26, 1801 -- Frances Taylor Madison and Robert Henry Rose married at Orange County, Virginia. 
1822 -- Robert Henry and Frances Taylor Madison Rose moved their family from Virginia to Alabama. 
October 4, 1823 -- Frances Taylor Madison Rose, age 49, died  at Alabama. 
March 6, 1836 -- James Madison Rose died during the siege of the Alamo, San Antonio, Texas. 
After June 28, 1836 (when James Madison died) -- eight of Robert Henry and Frances Taylor Madison Rose's children were alive: Hugh Francis Rose, Ambrose James Rose, Henry Rose, Samuel Jordan Rose, Robert Henry Rose, Erasmus Taylor Rose, Frances M. Rose, and Nelly Conway Rose Newman. 
James Madison, Sr. Wikipedia. Accessed by Michael Boynton on March 21, 2016 at 9:23 PM. 
The Dolley Madison Digital Edition. James Madison's Nieces and Nephews. Edited by Holly C. Shulman. Accessed by Michael Boynton on March 21, 2016 at 9:55 PM. 
The Dolley Madison Digital Edition. The Madison Family. Edited by Holly C. Shulman. Accessed by Michael Boynton on March 21, 2016 at 9:55 PM. 
Burke's Presidential Families of the United States of America, p.142.
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It may be possible to confirm family relationships with Fanny by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Fanny: