Sarah Catlett Madison was the daughter of James Madison and Eleanor Rose Conway. She was born August 17, 1764 in Montpelier, Virginia. Her brother James Madison Jr. was 4th President of the United States.
She married Thomas Macon January 30, 1790. They were the parents of nine children.
She passed away October 17, 1843 at Greenwood, Virginia.
Burke's Presidential Families of the United States of America, p.140.
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It may be possible to confirm family relationships with Sarah by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Sarah: