Isaac Martin was an early resident of Cincinnati, Ohio.
He passed away about 1802, as evidenced by his Hamilton County, Ohio probate record.
Sources
History of Cincinnati, Ohio : with illustrations and biographical sketches / compiled by Henry A. Ford and Kate B. Ford.
Chapter IX. Cincinnatis second decade
[1]
Abstracts of book 1 & book A, probate record, 1791-1826, Hamilton County, Ohio, page 20
[2]
Source: S430314121 Ancestry Family Trees Publication: Online publication - Provo, UT, USA: Ancestry.com. Original data: Family Tree files submitted by Ancestry members.Ancestry Family Tree Ancestry Family Tree 155800928
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DNA Connections
It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree: