Margaret was the daughter of Isaac Masters and Sarah (Kester) Masters. She married Lot Deming and they had 7 children.
Sources
1880 United States Federal Census - Knightstown, Henry County, Indiana
Genealogy of the Descendants of John Deming of Wethersfield, Connecticut: With Historical Notes by Judson Keith Deming Page 113
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DNA Connections
It may be possible to confirm family relationships with Margaret by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Margaret: