The connections among these various Monoes is not clear. It might be that there is no close relationship at all.
Children:
49677i.
Nathaniel Monroe (1770 to 1780-)
49678ii.
Monroe
49679iii.
Joseph Monroe (1800 to 1810-)
49680iv.
Monroe
Notes
Birth place: Ohio, United States Ohio was formed in 1803.
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DNA Connections
It may be possible to confirm family relationships with Unknown by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Unknown: