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It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Isaac:
I have a Mordica/Mordecai family tree that starts with my sons here in the Norfolk, Virginia area and goes directly through to Mordecai Moses Mordecai. I would like to exchange info with other members of this family.