Stephen Mosher is the son of Asa Mosher (1771 - 1843) and Bethiah Mosher (1771 - 1856), Quakers of New York. 
Stephen married Ruth Smith, born in Duchess county, New York, the daughter of Israel and Elsy (Southwick) Smith. Her parental grandparents were David and Mary (Yeomans) Smith.
Stephen and Ruth lived, first in Ohio, (where they had a "station" on the "underground railway") and then, circa 1864, when their youngest son was six, moved to Iowa. The family settled on a farm, long known as Edgewood, on the northern line of Muscatine couny, near its western limit. The property was occupied by the family for at least fifty-eight years and a granddaughter and her family were living on it at the time of the writing of the 1911 edition of History of Muscatine County.
The children of Stephen and Ruth Mosher were all born in Morrow County, Ohio and are as follows :
Elizabeth Mosher, born October 18, 1829, passed away on May 3, 1832.
Lemuel Mosher, born May 25, 1831, died May 8, 1832.
Elizabeth Jane Mosher, born May 20, 1833, married Isaac E. Schooley, a carpenter and farmer, the ceremony occurring on September 28, 1856.
Hannah Mosher, born July 5, 1853, and on the 16th of December, 1855, married James S. Barclay, a farmer and carpenter.
Ruth, born December 1, 1837, married December 9, 1858, to Matthias Wilson, a carpenter, farmer and soldier.
Mary S. Mosher born October 7, 1842, married March 12, 1868, to Blackburn Vore, a widower, who engaged in farming and blacksmithing in Fredericktown, Ohio.
Esther Ann, born March 15, 1845, married January 4, 1872. Wellington K. Eggleston, a widower of Boulder, Colorado.
Bethiah Elsy, was born in Morrow county, Ohio, August 11, 1850. She was married to A. D. Sinclair, of Muscatine, Iowa, on the 6th of February, 1873
Henry, born March 27, 1840, came to Iowa with his parents in 1853 and remained at home till his marriage to Henrietta D. Gibson, March 28, 1861.
Lemuel O. Mosher, born April 28, 1847, came with his parents to Iowa at the age of six. He was married to Lidorana D. White of Iron Hill, Iowa, September 29, 1870.
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