Frances was born about 1813. She passed away after 1850.
Sources
"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M657-74V : 12 April 2016), Frances Howard in household of Ephraim Howard, Harlan county, Harlan, Kentucky, United States; citing family 328, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
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DNA Connections
It may be possible to confirm family relationships with Frances by comparing test results with other carriers of her mitochondrial DNA.
Mitochondrial DNA test-takers in the direct maternal line: