Sarah was born about 1852. She was the daughter of William Nichols and Jemima Cole. She passed away after 1870.
Sources
"United States Census, 1870," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MXWL-DL6 : 12 April 2016), Sarah Nickle in household of William Nickle, Kentucky, United States; citing p. 18, family 124, NARA microfilm publication M593 (Washington D.C.: National Archives and Records Administration, n.d.); FHL microfilm 545,983.
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DNA Connections
It may be possible to confirm family relationships with Sarah by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Sarah: