He died in his teen age, about 15 or 16. He had no children.
Sources
Tazkirah-e Nizamani, by Prof. Abdul-Jabbar Qasim Nizamani, Nizamani Publication, Matli, Pakistan, March 2012
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DNA Connections
It may be possible to confirm family relationships with Muhammad Khan by comparing test results with other carriers of his ancestors' Y-chromosome or mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Muhammad Khan: