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DNA Connections
It may be possible to confirm family relationships with Mary by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mary:
Mary O'Brien/O'Brian, 1721-1790, the daughter of William O'Brien/O'Brian (son of William O'Brien and Mary Villiers) and Anne Hamilton (daughter of George Hamilton and Elizabeth Villiers) did not marry a James Fitzgerald; she married her cousin Murrough O'Brien, according to Cokayne:
Cokayne, G. E.; H. A. Doubleday & Lord Howard de Walden, eds. (1940). The Complete Peerage, or a history of the House of Lords and all its members from the earliest times, volume XIII: Peers created 1901 to 1938. 13 (2nd ed.). London: The St. Catherine Press. Volume X, p. 109
Perhaps the wife of this James Fitzgerald was a Mary O'Brien, but not this one, apparently.
Cokayne, G. E.; H. A. Doubleday & Lord Howard de Walden, eds. (1940). The Complete Peerage, or a history of the House of Lords and all its members from the earliest times, volume XIII: Peers created 1901 to 1938. 13 (2nd ed.). London: The St. Catherine Press. Volume X, p. 109
Perhaps the wife of this James Fitzgerald was a Mary O'Brien, but not this one, apparently.