In 1839 they all boarded the ship "Marion" for the voyage to America.
Elizabeth died on route and was buried at sea.
The trip was "stormy" and apparently nearly went down several times. The ship landed Aug 26, 1839. It took the families 35 days to travel from New York to Chicago by rail, and boat. From Chicago, the travelers proceeded by wagon to Rockford, IL. 
New Life in America
"James Picken had his share of troubles on leaving Scotland with the Giffins on July 4, 1839. His wife died on the ocean and was buried at sea, leaving the husband with three young children" They stayed in Ohio for a year, then came to the Scottish Settlement at Argyll. 
James married Mary Reid about 1847. They had three children:
Hugh R. 1848–1888
Mary (Patton) 1850-1934
Margaret (Andrew) 1851-1919
James passed away in 1888.
↑ Original data: Scotland, Births and Baptisms, 1564-1950. Salt Lake City, Utah: FamilySearch, 2013.
Name: James Pickan
Baptism Date: 20 Dec 1802
Baptism Place: , Southend, Argyll, Scotland
Father: Alexander Pickan
FHL Film Number: 1041076
Reference ID: - 2:16BJFLM
James Pickan, Marriage Date: 23 Jan 1833, Marriage Place: Southend,Argyll,Scotland. Spouse: Elisabeth Huie. FHL Film Number: 1041076
↑ "This information comes from a letter written by William Giffen, son of Andrew. William married Margaret Harvey, daughter of William Harvey who came to Argyle in 1841." Ralston's Ancestors Ship's List