He married Jane Brown in Scotland in 1829.
They had 13 children.
In July of 1839 they boarded the passenger ship "Jane" at Greenhock, Scotland and came to the United States. They traveled on to Illinois where they were one of the founding families of the Scottish settlement in Argylle, Illinois. 
In Caledonia, Boone Co., Ills, Nov. 20, 1875, Mr. GEORGE PICKEN, aged 69 years.
The deceased was a native of Argyleshire, Scotland.
He emigrated to America about 35 years ago and settled in Caledonia, where he has ever since resided. He was well known and highly respected, both in Boone and Winnebago counties. He raised a very respectable family of four sons and eight daughters. All of them live in the neighborhood and had the pleasure of hearing their father's last words of comfort to them.
The funeral, which took place on Monday last, was largely attended, the services being conducted by Rev. Dr. Ely, pastor of the Willow Creek Church, assisted by Rev. T. C. Easton, of Belvidere. Both of the reverend gentlemen spoke highly of the life of stern honesty and strict integrity lived by deceased. He was a consistent member of the church for upwards of half a century. He will be regretted by many, even outside of his own family circle.
↑ "New York Passenger Lists, 1820-1891," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:QVPF-MQS5 : 11 March 2018), Geo Picken, 1838; citing NARA microfilm publication M237 (Washington, D.C.: National Archives and Records Administration, n.d.); FHL microfilm .
↑ "United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M85N-Z8D : 12 April 2016), George Picken, Caledonia, Boone, Illinois, United States; citing family 38, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
↑ "United States Census, 1870," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M64Z-DT1 : 12 April 2016), George Piken, Illinois, United States; citing p. 29, family 219, NARA microfilm publication M593 (Washington D.C.: National Archives and Records Administration, n.d.); FHL microfilm 545,688.
Find A Grave: Memorial #53435348 Find A Grave, database and images (https://www.findagrave.com : accessed 16 August 2018), memorial page for George Picken (20 Nov 1804–20 Nov 1875), Find A Grave Memorial no. 53435348, citing Scottish Cemetery, Caledonia, Boone County, Illinois, USA ; Maintained by Amelia Crombie-Christy (contributor 46861625) .