Additional information gathered from: HISTORY AND GENEALOGY OF PIERSON FAMILIES; from 1550 to about 1900 - compiled by Merlin J. Stone 1 Jun 1909 - sent to me by Vikki Pierson Crosley. Thank you Vikki!!
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DNA Connections
It may be possible to confirm family relationships with James by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with James: