Cary and Mary Kizer (Keiser, Kiser) apparently had two daughters (Emeline and Hester) born between about 1843-1845. Mary could not be found in the 1850 US census or any subsequent enumerations; she apparently died prior to 1850.
Cary is found in Howard County, Indiana working as a farm laborer in the William Dorman residence. His children are not listed in the Dorman household and likely were placed with relatives so that Cary could work to support them.
No further children are recorded and Kizer researchers on Ancestry have not listed a subsequent marriage.
"Ohio, County Marriages, 1789-2016," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:XD47-JZR : 26 August 2019), Cary Rizer and Mary Elizabeth Pitzer, 21 Apr 1842; citing Marriage, Clinton, Ohio, United States, P 219, Franklin County Genealogical & Historical Society, Columbus; FHL microfilm.
"United States Census, 1850," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:MHJV-Y9P : 19 December 2020), Cary Riser in household of William Dorman, Center, Howard, Indiana, United States; citing family , NARA microfilm publication (Washington, D.C.: National Archives and Records Administration, n.d.).