Baltimore County was created on 30 Jun 1659 as an original county from unorganized territory.
Harford County was created on 17 Dec 1773 from Baltimore County.
The westernmost portion and the majority of My Lady's Manor was in what is now Baltimore County. The easternmost portion of My Lady's Manor was in what is now Harford County.
Sources
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St. John's Parish (Joppa, Maryland : Protestant Episcopal), Register of births, marriages and deaths, St. John's Parish, Joppa [Maryland] p46; database with images, FamilySearch (https://www.familysearch.org/ark:/61903/3:1:3Q9M-CS3L-Z95Y-1), image 352.
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St. John's Parish (Joppa, Maryland : Protestant Episcopal), Register of births, marriages and deaths, St. John's Parish, Joppa [Maryland] p253; database with images, FamilySearch (https://www.familysearch.org/ark:/61903/3:1:3Q9M-CS3L-Z9RX-N), image 455.
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DNA Connections
It may be possible to confirm family relationships with Mary by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mary: