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"United States Census, 1850," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:MDZF-KS8 : 22 December 2020), William Renfro in household of Mark Renfro, Benton Township, Osage, Missouri, United States; citing family , NARA microfilm publication (Washington, D.C.: National Archives and Records Administration, n.d.).
Note: need to add 3 wives and 9 children, more research need on burial.
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DNA Connections
It may be possible to confirm family relationships with William by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with William:
William https://www.ancestry.com/family-tree/person/tree/177569419/person/432305626709/facts
Renfro - Morgan county, Colorado https://www.findagrave.com/memorial/search?firstname=&middlename=&lastname=Renfro&birthyear=&birthyearfilter=&deathyear=&deathyearfilter=&location=Morgan+County%2C+Colorado%2C+United+States+of+America&locationId=county_284&memorialid=&mcid=&linkedToName=&datefilter=&orderby=r&plot=
Edit: correcting typo
edited by Gene Bird