Unknown was born about 1821. She was the daughter of Unknown Ryman. She passed away about 1899.
Sources
Mary's obituary
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DNA Connections
It may be possible to confirm family relationships with Unknown by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Unknown: