Hiram may have taken his family to Iowa with his parents and siblings. This 1850 Census record might be them:
"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MZ46-TTK : 12 April 2016), Hiram B Scott, Rome, Jones, Iowa, United States; citing family 739, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
Sources
"Ohio Marriages, 1800-1958," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:XDZJ-MXV : 10 February 2018), Hiram B. Scott and Elizabeth Gilbert, 12 Jan 1843; citing Columbiana Co., Ohio, reference 2:3WT2KFF; FHL microfilm 927,766.
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This week's connection theme is the Puritan Great Migration.
Hiram is
13 degrees from John Winthrop, 13 degrees from Anne Bradstreet, 13 degrees from John Cotton, 13 degrees from John Eliot, 12 degrees from John Endecott, 13 degrees from Mary Estey, 12 degrees from Thomas Hooker, 12 degrees from Anne Hutchinson, 14 degrees from William Pynchon, 13 degrees from Alice Tilley, 10 degrees from Robert Treat and 10 degrees from Roger Williams
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good catch - was a bit of a typo, but all fixed now