She married 1874 Henry Cole (1850-1935). (Find a Grave)
Sources
↑ 1851 census has Matilda age 1, Susan age 4. However, since the children are usually listed in age order, this is more likely 4 months.
↑ Find A Grave, database and images (https://www.findagrave.com : accessed 21 March 2020), memorial page for Susan Jane Sears Cole (1850–7 Jan 1907), Find A Grave Memorial no. 190670325, citing Edson Cemetery, Lowell, Middlesex County, Massachusetts, USA ; Maintained by LMR (contributor 46926975) .
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DNA Connections
It may be possible to confirm family relationships with Susan by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Susan: