If the Lettice Shakespeare who married John Drake was the Lettice, daughter of Henry, then William Shakespeare was her uncle.
the marriage of John Sr. and the baptism of his children John, Job and Esther has been found in Hampton-in-Arden, Warwickshire. John, Jr. was baptized 25 Aug 1616, son of John Drake and Lettice Shakespeare. (Lettice d. 1623 and Elizabeth Rogers was his second wife.)
Lettice Shakespeare was buried on 10 Nov 1623 in Hampton in Aden, Warwick, England. Likely connected as a cousin of some sort to the famous William, who was born in Warwick in 1564 and whose mother's name was Mary Arden. WC connects as daughter of Henry, William's uncle, but if source is IGI, that record says she died in 1595.
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Lettice is 20 degrees from AJ Jacobs, 23 degrees from Carol Keeling, 12 degrees from George Washington and 17 degrees from Queen Elizabeth II Windsor on our single family tree. Login to find your connection.