Not much is known of Margaret as yet.
Her parents were Peter Spence and Jean Cumming.
Nothing is known about them as yet.
However they were married March 04 1725.
Sources
From a source called "The Winchesters" updated 3rd Jan 2015 and downloaded 6th May 2015 and 7th May 2015.
www.s1952.tribalpages.com
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DNA Connections
It may be possible to confirm family relationships with Margaret by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Margaret: