"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MX77-N6X : 12 April 2016), Margs Sprout in household of Jacob Sprout, Jackson, Seneca, Ohio, United States; citing family 71, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
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DNA Connections
It may be possible to confirm family relationships with Margaret by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Margaret:
Is this the same Margaret (Sprout) Cox that is the daughter of Jacob Sprout II and Margaret (Long) Sprout and sister of William and numerous other siblings?