Published Vital Records of Norwich, Connecticut (Online as a Google Book) for the birth and marriage.
Perkins, Mary E., Old Houses of the Antient Town of Norwich, Norwich Connecticut, 1895. (can be downloaded as an E-Book)
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It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree: