Daughter of William Tuttle and Margaret/Maggie (Nancy?) Richardson
Sources
"Kentucky, Vital Record Indexes, 1911-1999," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:QKH2-697M : accessed 2 May 2016), Katherine Tuttle, 29 Oct 1925; citing Birth, Estill, Kentucky, United States, Kentucky Department for Libraries and Archives, Frankfort.
"United States Census, 1930", database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:XM68-B2X : accessed 2 May 2016), Catherine Tuttle in entry for William N Tuttle, 1930.
"United States Census, 1940," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:K7R2-NLW : accessed 2 May 2016), Katherine Tuttle in household of W N Tuttle, Magisterial District 5, Estill, Kentucky, United States; citing enumeration district (ED) 33-12, sheet 4A, family 64, NARA digital publication T627 (Washington, D.C.: National Archives and Records Administration, 2012), roll 1301.
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DNA Connections
It may be possible to confirm family relationships with Katherine by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Katherine: