"United States Census, 1850," index and images, FamilySearch (https://familysearch.org/pal:/MM9.1.1/M658-74X : accessed 09 May 2014), Catharine Tye in household of George W Tye, Knox county, part of, Knox, Kentucky, United States; citing family 1058, NARA microfilm publication M432.
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DNA Connections
It may be possible to confirm family relationships with Catharine by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Catharine: