Harry Truman is the great, great, great grand son of Edward Tyler.
Edward Tyler was the son of Elizabeth Duvall and Edward Tyler. He was also the progenitor of the Tyler family in Jefferson County, Kentucky (Louisville area). He was married to Ann Langley and they reportedly had 10 children. The Tyler Cemetery is also known as the Edward Tyler Cemetery after him.
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It may be possible to confirm family relationships with Edward by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share DNA with Edward: