Winifred was born about 1820. She was the mother of Rebecca, Susan W, John C, Sarah E, James E, and Laura E
Sources
1860 US Census
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DNA Connections
It may be possible to confirm family relationships with Winifred by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Winifred: