Charles Emmanuel de Savoie, 3rd Duc de Nemours, (1567 ? July 1595) was the son of Jacques of Savoy and Anne of Este, the widow of Francis, Duke of Guise. As a child he was known as the prince of Genevois. He was the Duke of Nemours from 1585 to his death in 1595, during the French Wars of Religion.
Charles Emmanuel was duke at a volatile time, and subsequently was involved in many political intrigues, mostly by his relationship on his mothers side with the House of Guise. The Duke of Guise was one of the leaders of the Catholic League opposing the Huguenots, and Charles Emmanuel sympathised with their cause. However, after the assassination of Henry I, Duke of Guise and his brother the Cardinal of Guise, Charles Emmanuel was imprisoned by the Huguenots in 1588, but was able to escape.
He was to fight the Huguenot forces for some years; he fought at the Battle of Arques in 1589. That same year, Charles Emmanuel was the governor of Paris, as the Huguenot forces, led by Henry of Navarre besieged Paris. During the siege, King Henry III of France perished, and Henry of Navarre soon declared himself King Henry IV of France. Charles Emmanuel escaped, and fought the newly proclaimed King at the Ivry in 1590, which was a decisive loss for the Catholic League.
After the defeat, Charles Emmanuel strongly disagreed with his half-brother and long-time ally Charles of Lorraine, Duke of Mayenne (also of the House of Guise), who advocated conciliation with Henry IV. Charles Emmanuel withdrew to his government in Lyonnais, where he endeavoured to make himself independent from the French crown. He was imprisoned, however, in the chateau of Pierre-Encise by the archbishop of Lyon. Again, he successfully escaped, and decided to attack Lyon. The intervention of the Constable de Montmorency thwarted his attack however, and his attempt at independence failed.
He died at Annecy in 1595, leaving the Duchy of Nemour to his brother Henri de Savoie.
It may be possible to confirm family relationships with Charles Emmanuel by comparing test results with other carriers of his ancestors' Y-chromosome or mitochondrial DNA.
However, there are no known yDNA test-takers in his direct paternal line.
Mitochondrial DNA test-takers in the direct maternal line: