Since Margaret's daughter was born in 1784, Margaret was probably born before 1766.
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DNA Connections
It may be possible to confirm family relationships with Margaret by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Margaret:
~0.78% ~6.25%Ronald Yates :
23andMe, GEDmatch A861466[compare], yourDNAportal RON50ab2e57
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AncestryDNA, GEDmatch A861466[compare], yourDNAportal RON50ab2e57, Ancestry member ronyates47
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Family Tree DNA Family Finder, GEDmatch A861466[compare], yourDNAportal RON50ab2e57, FTDNA kit #181239