William married Mary Cook in 1751, and had 2 children
Sources
The Book of Daniel Hovey and His Descendants, page 29
Wadsworth, Horace Andrew, Two Hundred and Fifty Years of the Wadsworth Family in America (Lawrence, Mass. Printed at the Eagle Steam Job Printing Rooms. 1883 [GenealogyLibrary.com]).
Lucius Barnes Barbour, Families of Early Hartford, Connecticut (Baltimore: Genealogical Publishing Co., 1977 reprint), p 615-617.
Twitchell/Barton family genealogy tree.
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DNA Connections
It may be possible to confirm family relationships with William by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with William: