Mattie was born about 1840. She passed away before 1940.
Sources
"South Carolina Deaths, 1915-1965," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:N9VS-RW1 : 19 July 2017), Elias Edward Horry, 18 Jul 1938; citing , Horry, Elias Edward, 1938, Department of Archives and History, State Records Center, Columbia; FHL microfilm 1,943,856.
John Webb household, 1850 US Census, Beaufort County, South Carolina, population schedule, St Luke's Parish, page/sheet 51 & 52, dwelling 260, family 260, line 39-42 & 1-2; National Archives.
Mary Shubrick Horry Eppes, "M S Horry Eppes Genealogy Notes", Died at Woodside, North Santee at 10 3/4 o'clock on the 24th of Nov 1878 - Mattie Webb Horry, wife of Edward S. Horry, aged 35 years, 5 months and 15 days. Her disease was Scarlet Fever. She leaves a bereaved husband and 5 children to mourn the loss of a most devoted and affectionate wife and mother. Thy Will Be Done, O Lord. Her remains rest at Milldam.
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DNA Connections
It may be possible to confirm family relationships with Mattie by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mattie: