Her and her husband, James Loring Gates, had no children.
Sources
"Massachusetts, Town Clerk, Vital and Town Records, 1626-2001," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:Q29G-6SSP : 20 May 2022), Adeline N Wiley, 28 Oct 1826; citing Birth, Charlestown, Boston, Suffolk, Massachusetts, United States, Massachusetts Secretary of the Commonwealth, Boston; FHL microfilm 007009468.