It may be possible to confirm family relationships with Caleb by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree:
Caleb Wilhoit Died in Boone, Co. Ky. April 1, 1831. Born, Nov. 1783 is correct. These dates are on his Tombstone which was found by myself in the Family Plot in Florence, Ky. Mr. Charles Baxter of Mainville, Ohio is a surviving ( Jan. 2016) Family relative of Hester Ann Wilhoit, 1st. Child of his Son Milton.