John was born about 1851. He passed away before 1951.
Sources
"United States Census, 1910," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MLM3-46J : accessed 10 March 2020), Oscar A Willis in household of John R Willis, Pike Creek, Shannon, Missouri, United States; citing enumeration district (ED) ED 88, sheet 3B, family 51, NARA microfilm publication T624 (Washington D.C.: National Archives and Records Administration, 1982), roll 824; FHL microfilm 1,374,837.
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DNA Connections
It may be possible to confirm family relationships with John by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with John: