Anne of York, Duchess of Exeter (10 Aug 1439 – 14 Jan 1476)
p. Richard, 3rd Duke of York and Cecily Neville
m.1 1447 Henry Holland, Duke of Exeter. Divorced 1472.
dau. Anne Holland (c.1455-btw 26 Aug & 06 Jun 1447)
m. Oct 1466 Thomas Grey, 1st Marquess of Dorset
m.2 1474 Thomas St. Leger
dau. Anne St. Leger (14 Jan 1476 – 21 Apr 1526)
Burial: 1 Feb 1476 St. George's Chapel, Windsor
Anne of York was the second child and oldest surviving daughter of Richard, 3rd Duke of York and Cecily Neville. She was an elder sister of:
Edward IV; Edmund
Earl of Rutland
Elizabeth of York
Duchess of Suffolk
Margaret, Duchess of Burgundy
George Plantagenet, 1st Duke of Clarence
Richard III of England
1147: Marriage to Henry Holland
Anne married Henry Holland, 3rd Duke of Exeter. They had one daughter, Anne Holland who married Thomas Grey, 1st Marquess of Dorset.
During the Wars of the Roses, Exeter sided with Lancasters against the York. Exeter was a commander at the Lancastrian victories of Wakefield and the second Battle of St. Albans. He was also a commander at the Battle of Towton, and fled to Scotland after the Lancastrian defeat. He later joined the exiled Margaret of Anjou in France.
On 4 March 1461, her younger brother was declared King Edward IV in London. Exeter was attainted but the king gave his estates to Anne, with remainder to their daughter Anne Holland. Anne and Exeter separated in 1464 and divorced in 1472.
Her daughter, now a wealthy heiress, was married in October 1466 at Greenwich Palace to Thomas Grey, 1st Marquess of Dorset, son of Elizabeth Woodvylle and her first husband. Lady Dorset died sometime between 26 August 1467 and 6 June 1474 without issue. Grey then married the young heiress Cecily Bonville, and had children.
In 1467, the king extended the remainder of most of Exeter lands to Anne and her heirs (if remarried any future children could inherit).
During the Readeption of Henry VI, Anne remained loyal to her brother Edward, and worked to persuade her brother George, Duke of Clarence, to abandon the Lancastrian cause. Her arguments had some effect, so she played a part in Edward's restoration.
1474: Marriage to Thomas St. Leger
Anne's married her second husband in 1474 Thomas. Sadly, she died giving birth to their only daughter, Anne St. Leger (14 Jan 1476 – 21 Apr 1526) heiress to the Exeter estates.
"Royal Ancestry" 2013 by Douglas Richardson Vol. V. page 455
ANNE PLANTAGENET, born at Fotheringhay Castle, Northamptonshire 10 August 1439. She married (1st) before 30 July 1447 HENRY (or HARRY) HOLAND (HOLLAND), Knt., Duke of Exeter, Earl of Huntingdon and Ivry [see EXETER 11.I], joint Admiral of England, Ireland, and Aquitaine, 1446, joint Constable of the Tower of London, 1447, Lord and Castellan of Lesparre and L'Esparrois, 1447, Constable of Fotheringhay Castle, 1459, son and heir of John Holand (Holland), Duke of Exeter, Earl of Huntingdon and Ivry, by his (1st) wife, Anne, daughter of Edmund Stafford, K.G., K.B., 5th Earl of Stafford [see EXETER 11 for his ancestry]. he was born in the Tower of London 27 June 1430. He resided at King's Hall, Cambridge in 1439-40 to 1441-2. They had one daughter, Anne (wife of Thomas Grey, K.G., K.B., 1st Marquess of Dorset, Lord Ferrrers of Groby) [see GROBY 17]. He and his wife, Anne, were granted a papal indult for a portable altar in 1455. His wife, Anne, was admitted to the fraternity of St. Nicholas in London in 1446. She presented to the church of Blagdon, Somerset in August 1472. They were divorced 12 Nov. 1472 (he drowned Sept. 1475). She married (2nd) about 1472/3 THOMAS SAINT LEGER Knt. ... son of John Saint Leger, Esq., of Ulcombe, Kent, Sheriff of Kent, by Margery, daughter and heiress of James Donet [see RAYNSFORD 11.i.a for his ancestry]. They had one son, Anthony, and one daughter, Anne.
Anne Plantagenet died 12 (or 14) Jan. 1475/6. He presented to the church of Blagdon, Somerset in 1479. He was present at the funeral of King Edward IV in 1483. SIR THOMAS SAINT LEGER was the chief instigator of the Buckingham rising in Surrey against King Richard III, in 148. He was taken at Torrington and beheaded at Exeter, Devon 12 Nov. 1483.
"Royal Ancestry" 2013 by Douglas Richardson Vol. IV. page 461
Ross, Charles (1997). Edward IV. Yale English monarchs (illustrated ed.). Yale Univ Press. pp. 336–337. ISBN 0300073720.
"Ancestors/Descendants of Royal Lines" (Contributors: Manuel Abranches de Soveral, Reynaud de Paysac, F.L. Jacquier <Genealogy of Lewis Carroll, Justin Swanstrom, The Royal Families of England Scotland & Wales by Burkes Peerage; Debrett's Peerage & Baronage; Table of descendants French Canadian Genealogical Society>, H.R. Moser <Burke Peerage>, L. Orlandini, O.Guionneau, L.B. de Rouge, E. Polti, A.Terlinden <Genealogy of the existing British Peerage, 1842>, L. Gustavsson, C. Cheneaux, E. Lodge, S. Bontron <Brian Tompsett>, R. Dewkinandan, C. Donadello) http://geneastar.org.
The royal lineage of our noble and gentle families, pg 181 
It may be possible to confirm family relationships with Anne by comparing test results with other
carriers of her mitochondrial DNA.
Mitochondrial DNA test-takers in the direct maternal line: