Magdalena was born about 1800. She is the daughter of Unknown Fischler.
Assuming she is Bernard Fischler's sister...may have been one of the 6 family traveling with him from Switzerland.
Sources
Referenced as witness at Bernard's wedding and sponsor at many of the children's baptisms.
"United States Census, 1860", database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M4SW-B24 : 18 March 2020), Magdelene Winterholter in entry for George Winterholter, 1860.
U.S. City Directories, 1822-1995. M Winterhalter, Female, Residence: 301 W 4th, Wilmington, Delaware, USA. Spouse: George Winterhalter. Wilmington, Delaware, City Directory, 1865
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DNA Connections
It may be possible to confirm family relationships with Magdalena by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Magdalena: