Descendant of Francis Cooke (abt. 1583 - 1663) via father Benjamin Cooke and James Chilton (abt. 1555 - 1620) via mother Mary Gray.
Sources
Ralph V. wood, Jr., comp., Mayflower Families Through Five Generations, Francis Cooke, Volume 12, (Plymouth: General Society of Mayflower Descendants, 2015), p. 447-8
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DNA Connections
It may be possible to confirm family relationships with Lettice by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Lettice: