There are conflicting reports about who is mother is - Geni says his mother was Agnes Unknown LNAB; Family Search says his mother was Jane Butcher. I believe his mother was Jane Butcher because
the match between William W Wilkinson and Mary Agnes Van Landingham came after Jacob Butcher Wilkinson was born AND
his middle name seems to be a tribute to Jane Butcher's maiden name which would make sense for Jane's son.
Sources
Census Records:
"United States Census, 1830," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:XH5X-8RN : 9 September 2017), Jacob Wilkerson, Perrysburg, Wood, Ohio, United States; citing 325, NARA microfilm publication M19, (Washington D.C.: National Archives and Records Administration, n.d.), roll 142; FHL microfilm 337,953.
"United States Census, 1850", Elizabeth Township, Jo Davies County, Illinois, Family 1223, Jacob Wilkinson, head of household.
"United States Census, 1860", database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M664-V54 : 13 December 2017), Alfred Wilkerson in entry for Jacob Wilkerson, 1860. (in Kansas)
"Iowa, County Marriages, 1838-1934," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:KLW5-76D : 4 November 2017), Jacob Wilkinson in entry for Benjamin T Wilkinson and Elizabeth Cox, 01 Dec 1880, , Fremont, Iowa, United States; citing reference , county courthouses, Iowa; FHL microfilm 1,255,492.
"Iowa, County Marriages, 1838-1934," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:KLWP-6RV : 4 November 2017), Jacob Wilkinson in entry for John Pugh and Emma E Wilkinson, 01 Mar 1881, , Fremont, Iowa, United States; citing reference , county courthouses, Iowa; FHL microfilm 1,255,492.
"Nebraska Marriages, 1855-1995," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:Q298-RJ3M : 18 January 2020), Jacob Wilkinson in entry for James E. Wilkinson, 24 Dec 1884; citing Marriage, Otoe, Nebraska, United States, Nebraska State Historical Society, Lincoln; FHL microfilm 1,977,799.
Death Records for his children:
"Iowa, Death Records, 1904-1951," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:QP24-V8SN : 18 October 2019), Jacob Wilkinson in entry for Rachel A Betchel, 6 May 1916, Iowa, United States; citing certificate #, State Historical Society of Iowa, Des Moines; FamilySearch digital folder 102869846.
Johnson, 15 Oct 1906, Buchanan, Iowa, United States; citing certificate #1000341, State Historical Society of Iowa, Des Moines; FamilySearch digital folder 102842704.
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DNA Connections
It may be possible to confirm family relationships with Jacob by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Jacob: