Theodora was born in Constantinople at 3 after midnight on 15 January 1096, the fourth of five daughters, and seventh child overall, of Emperor Alexios I Komnenos (r. 1081–1118) and Irene Doukaina. In c. 1111 she married Constantine Kourtikes, but her husband died soon after marriage. Theodora is mentioned as a widow in 1118 and the marriage remained childless. In 1122 after the death of Alexios I, she married a second time, to Constantine Angelos, a minor noble from Philadelphia. He was exceedingly beautiful, but Empress Irene disapproved, and it seems to have soured her relations with Theodora, who is listed last and with the least favourable provisions in the typikon that Irene granted to the Kecharitomene Monastery. Theodora is mentioned for the last time in October 1136, and it is unknown when she died.
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