Margaret was the daughter of Nathaniel & Margaret (Gibbs) Appleton
She married as his second wife, Joshua Prentice, son of Henry & Elizabeth (Rand) Prentice, about 1755 at Cambridge, Middlesex, MA Bay - parents of Appleton & Margaret
Appleton, William. Family Record of John Appleton and Elizabeth (Rogers) Appleton, of Ipswich, Mass., The New England Historical & Genealogical Register (New England Historic Genealogical Society, Boston, Mass., 1873) Vol. 27, Page 37.
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