She married in 1484 (while probably still in her early teens[1]), Federico Sforza, 8th Conte di Santa Fiora, son of Guido Sforza, 7th Conte di Santa Fiora, and his wife, Francesca Farnese.
They had six children:
Bosio II Sforza, succeeded his father as 9th Conte di Santa Fiora;
Ippolita Sforza, married (1) 1504, Federica Farnese, Signore di Canino e Gradoli; (2) Alessandro Gonzaga, of the family of Lords of Vescovato; she died at Canino in 1543;
Alfonso Sforza, born 1493, appointed Archbishop of Benevento 8 April 1521 and died before 1528;
Daughter (hame unknown), married Girolamo Marchese del Monte Santa Maria;
Ascanio Sforza, Knight of the Order of Malta 1548, Commendatore of San Giovanni di Viterbo and San Massimo di Bagnoriea, Prior of Hungary, died 1553;
Elena Sforza, married don Antonio Maria Piccolomini, 1st Duca de Montemarciano and Signore di Camporsevoli.
Federico, died about 1535, but when Bartolomea died is unknown.
Footnotes
↑ her parents were married in 1467 and Bartolomea doesn't appear to have been the eldest child
Sources
Societa Genealogica Italiana SGI, (2014), Genealogie delle famiglie nobili del Mediterraneo; (http://www.genmarenostrum.com : viewed 31 August 2014) - Particularly Orsini: del Balzo e di Pitigliano; & Sforza
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