Memorial on Find a Grave has a note stating that the cemetery records clearly show 6 April as being the month and day of birth, but that the year of 1833 is 'iffy'. I think the date listed here is likely correct as Catherine's mother would be well beyond child bearing years in 1833. There's no record (so far) of her father having had a second wife.
Sources
"Find A Grave Index," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:QVLB-7YFL : 11 July 2016), Catherine Drum Walthour, 1876; Burial, Irwin, Westmoreland, Pennsylvania, United States of America, Brush Creek Cemetery; citing record ID 105132008, Find a Grave, http://www.findagrave.com.
"Pennsylvania, County Marriages, 1885-1950," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:VF48-Q4B : 23 September 2017), Catharine Walthour in entry for Samuel Walthour and Sophia Kistler, 29 Aug 1889; citing Marriage, , Westmoreland, Pennsylvania, United States, various county courts and registers, Pennslyvannia; FHL microfilm 1,316,385.
History of Allegheny County, Pennsylvania|History of Allegheny County, Pennsylvania]] (A. Warner & Co., Chicago, 1889, Part 2: p. 641)
"Pennsylvania, Historical Society of Pennsylvania, Births and Baptisms, 1520-1999", database, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:6CTT-WLW2 : 11 January 2021), Margaretta Drom in entry for Catherina Drom, 1796.
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DNA Connections
It may be possible to confirm family relationships with Catherine by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Catherine: